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Alyaa Shmara Selected Research

CB-5083

1/2022VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy.
1/2021A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6.

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Alyaa Shmara Research Topics

Disease

2Proteostasis Deficiencies
01/2022 - 01/2021
2Neoplasms (Cancer)
01/2022 - 01/2021
1Frontotemporal Dementia (Semantic Dementia)
01/2022
1Toxic Optic Neuropathy
01/2022
1Muscular Diseases (Myopathy)
01/2022
1Osteitis Deformans (Paget's Disease of Bone)
01/2022
1Vision Disorders (Hemeralopia)
01/2021
1Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia
01/2021
1Photophobia (Light Sensitivity)
01/2021

Drug/Important Bio-Agent (IBA)

2Valosin Containing ProteinIBA
01/2022 - 01/2021
2CB-5083IBA
01/2022 - 01/2021
1Retinaldehyde (Retinal)IBA
01/2022
1Merozoite Surface Protein 1 (MSA1)IBA
01/2022
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
01/2021
1Pharmaceutical PreparationsIBA
01/2021